2-Mercaptoethanol Treatment Improves Measurement of an IgMκ M-Protein by Capillary Electrophoresis

Serum protein electrophoresis by CZE 2000 clinical capillary electrophoresis system.

We compared the automated Paragon 2000 clinical capillary zone electrophoresis (CZE) system with two manual methods, agarose electrophoresis (AGE) and cellulose acetate electrophoresis (CAE). Reference intervals in healthy adults were determined for each method. When compared with AGE and CAE, CZE gave substantially higher reference values for the alpha1-globulin fraction. With CZE, within-run ...

Measurement of nephrolithiasis urinary markers by capillary electrophoresis.

A previously developed method for screening organic acidurias by capillary electrophoresis has been validated for oxalate and citrate measurement in urine. Sample pretreatment is minimum, just acidification and centrifugation. Detection is by direct UV. Validation parameters of the method can be considered adequate. Response is linear for both analytes in standards and samples. The assayed rang...

Capillary Electrophoresis Improving Clinical Measurement of Clozapine

Optimization of serum protein separation by capillary electrophoresis.

* Author for correspondence. 2. Lewellen U, McCurdy HH. A novel procedure for the analysis of drugs in whole blood by homegeneous enzyme immunoassay (EMIT). J Anal Toxicol 1988:12:260-4. 3. Manca D, Ferron L, Weber JP. A system for toxicological screening by capillary gas chromatography. Chin Chem 1989;35:601-7. 4. Hawks R, Chiang C, eds. Urine testing for drugs of abuse. NIDARes Monogr 73, Roc...

Studies of carbohydrate-protein interaction by capillary electrophoresis.

T he high cap abilities of cap i l l a ry electro p h o resis in both separation and detection have been well recognized. It allows high resolution separation with theoretical plate numbers often exceeding several hundred thousands and rep ro d u c i ble quantifi c ation by on-cap i l l a ry detection. In addition to these adva n t age s , c ap i l l a ry electrophoresis has a characteristic fe...